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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are typically characterized by a focus on practical aspects of the research design, like recruitment and consent in adherence, as well as the use of standard equipment.

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A pragmatic trial that uses various investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is required for pragmatic trials to be able to prove their validity, and it also helps to reduce the chance of bias in the results. However, too much heterogeneity could cause issues with the design of the trial.

Pragmatic Play Pragmatic Play, one of the major players in the live casino market, provides an array of traditional table games, including Blackjack and Roulette. Pragmatic Play's live studios in Romania and Malta provide a genuine gambling experience for customers and offer an extensive selection of virtual betting options. The company has also developed numerous interactive game shows that make gambling online enjoyable. Some of these shows are hosted live, while others include famous people from the industry.

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Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are usually commissioned by policymakers and practitioners to guide their decisions. They can be used to determine the cause-effect relationship of an intervention and 프라그마틱 슬롯 its effects. However, they should not be used in lieu for 프라그마틱 정품 확인법 the use of explanation studies.

The pragmatism concept is controversial and there are concerns about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 proposed the distinction between explanation studies, which confirm a physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in the decision-making process for policy and practice. They also proposed an approach to pragmatic trials, which they called PRECIS.2 This tool sought to define the features of a pragmatic trial, including the recruitment process, the design and implementation of the intervention, and follow-up.

The number of pragmatic trials is increasing. A recent Medline query using the keywords naturalistic and pragmatic, restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to note that the majority of these trials were conducted in primary care settings.